I always get some sort of eye strain, headaches, nausea side effects from a new screen (lcd and oled). I persevere, and it usually gets better after about 2 weeks.
The new m5 iPad isn’t as bad as I thought it was going to be, but I am getting side effects (mainly headaches, eye strain and my tinnitus is worse).
This started about 10 years ago when I purchased a MacBook Pro retina. Ended up sending it back as the nausea was really bad. Before that, I was never affected by screens.