Researchers at Joslyn Diabetes Center in Boston have have a genetic trigger, "Master Switch" in the liver of obese adults. It causes a low level inflammation that can produces Type II or adult type diabetes. Research than a low cost aspirin type medication can reduce this inflammation. This treatment has been found to work in mice. Human testing is underway.
http://www.boston.com/news/globe/health_science/articles/2005/01/31/researchers_find_diabetes_trigger_possible_fix/
http://www.boston.com/news/globe/health_science/articles/2005/01/31/researchers_find_diabetes_trigger_possible_fix/