So I downloaded both images, and compared them in Photoshop. Do I correctly understand you to mean that non-retina optimized programs look "meh" in comparison to programs that are optimized, and that the problem is having both on screen at once and finding the difference jarring? Or do you mean that non-optimized programs are objectively "meh"?
When I increase the size of both images so that icons in the bottom toolbar are equal in size, they appear to be identical (looking at the "italics" icon, "Page Properties..." button, etc). I don't see any fuzziness in the retina screenshot that isn't there in the non-retina. Of course, the non-retina screenshot is from a 1680x1050 display, while the retina screenshot is effectively 1440x900, so if you make both full screenshots the same size (as opposed to matching the size of Dreamweaver UI elements), of course the non-retina looks sharper: the same number of effective pixels are in a smaller amount of space. That doesn't seem to be a problem in rendering on the retina screen though, the issue would be identical between 15.4" non-retina 1680x1050 and 1440x900 screens.
Is there something I'm missing? Or does the problem not really show up in screenshots, because it's an effect of the retina screen's 4:1 pixel swap making the Dreamweaver UI appear sharper, thus making its lower resolution more apparent than on a non-retina screen?
Anyway, thank you for posting the screenshots. I'm very interested in this issue, and seeing hard evidence is very helpful. If you have the time, could you post a similar pair of shots, but with the retina screen at an effective 1680x1050, so we could see how it looks when all UI elements are taking up the same amount of screen real estate? Thanks again.