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Was having this problem in Safari and Chrome. Temporary solution for me was to disable swipe left/right gestures in system preferences and creating said gestures in BetterTouchTools for all of my browsers. Hope this issue gets fixed soon.
 
This Fix Safari Freezing 10.9.2

http://discussions.agilebits.com/di...fari-on-os-x-10-9-mavericks-developer-preview

In Finder, select Go > Go to Folder… from the menu bar. Copy and paste the following path into the input box and then press Return:

~/Library/Safari
Remove both the Extensions and Databases folders. This will require you to reinstall all extensions but will also resolve the problem.

It seems that 10.9 may not properly migrate some data during the upgrade process.
 
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