I use one of each at my two offices, both on Comcast Business Class Deluxe 75 (75/10) and attached to a 4th Gen AE with wireless off, which serve an AC AE that provide wireless.
Both modems use the same firmware - the 6141 is very finicky with fluctuating power levels, and the 6121 is and has been rock solid. Comcast bought my 6141 modem via a buyback and I'm not paying a rental fee for it either, and it's there and it's working - it's my 3rd 6141 and when it craps out I'll be getting a 6121 to replace it; the newer 6183 hasn't been certified for Comcast BC.
IMO you're not missing anything, I'd wait to get the 6183 when it finally goes on sale - the 6141 is getting discounted for a reason. I got mine for free and it's still too much...