MBP M1 Max w/ Sequoia 15.7.3 here. I have Mail running all the time. Never quit the application. Got over 20K messages between Inbox and folders in iCloud mail. My uptime is currently 37 days. I honestly can't remember the last time Mail crashed on me. It's been years.
Tell us more about the type of email accounts you have configured and how many messages in your accounts.