What's your budget?
If it's lower than $200, I'd recommend a multimedia sound system, like Logitech's or Klipsch's.
If your budget is between $200 and $500, I'd recommend a Home-Theater-in-a-Box, like the Onkyo HT-590 or HT-790.
If your budget is between $500 and $1000, I'd recommend either a 5.1 system with the entry-level systems at your local Best Buy or Circuit City, or a higher-quality 2.1 system. Consider an Onkyo AVR + Polk Monitor Series (Circuit City), or a Pioneer AVR + JBL Studio Series (Best Buy) or the the SVS SBS-01 + SVS Sub + Receiver (svsound.com).
If your budget is between $1000 and $2000, I'd recommend visiting a home theater store and get an AVR from Denon, Marantz, Pioneer Elite, or HK, with a speaker system from Paradigm, Ascend Acoustics, Bowers & Wilkins, Vienna Acoustics, Klipsch, KEF, NHT, Monitor Audio etc. I'd heartily recommend the Paradigm Monitor v5 series or the B&W 600 series.
If your budget is between $2000 or more, you should know what you're getting yourself into and probably wouldn't be asking your question here, I'm assuming...
BOSE would only be a consideration if space is an absolute premium. Dollar-for-dollar, the sound quality is not that great, compared to these options. Bang & Olufsen would only be a consideration if style is an absolute premium. Dollar-for-dollar, they are poor performers compared to these options as well.