Hd Homerun was a pain to setup. I just bit the bullet and bought the slingbox 350. It cost me about 178 at frys, but you can buy it on ebay for 125.
From what I read the slingbox 350/500 are the easiest to setup. I pretty much plugged in all the correct wires and powered it up. From that point I created my account and log on to the slingbox site. And I was ready within 5 minutes. There was no real setup ( like opening ports, adding firewall exceptions or anything technical). I was really impressed with the clarity and signal. Not to mention I have an unlimited Verizon data plan so I have been able to watch TV everywhere I go now. I hit 10gbs within a three days.
Warning though: Don't buy a slingbox if your internet connection upload speeds are under 256k.