Short answer is NO. macOS is not Windows! As all applications are self contained (you can right mouse click on them and "show content" to see what has been packed within), you'll find macOS system is always running fast no matter how many apps have been installed (a huge advantage over Windows : )
There are some residual data left behind after you simple drag the application to the trash to delete, search ~/Library/Application/Support/
AppCleaner, Omni Remover and other similar Uninstaller utility is made to librate your time and do the clean app removal for you.