That depends on what you're looking for in your next pair of earbuds. As an all-rounder for general use that does everything well enough to excellent, the APP3 are a contender for the best in market, especially for those using Apple devices. APP3 is considered among the best at ANC (with Bose QC2 and Sony WF-1000XM5 slightly better, but not by much). They're great for calls and conferencing, with excellent voice quality on both ends. Then, they have extra features that few if any other brands have, like live translation, heartbeat monitor and hearing aid. So as a Swiss-army knife of earbuds, APP3 is among the best 2 or 3 options.
When it comes to sound quality for music listening, APP3 is nowhere near the best, especially if price doesn't matter. In this department, APP3 is just pretty good. In the current market, there's a trade-off in earbuds between ANC and sound quality. There's not a single product that is best at both. Options like the Noble Prestige Encore and Geekfly Vitas, among others, will deliver vastly superior sound quality to the APP3. However, the Noble's ANC is just average, and the Vitas have no ANC at all (but decent passive noise cancelling). So for the audiophile with unlimited budget, I would recommend getting at least 2 pairs of earbuds: an APP3 (or Bose or Sony) for practical stuff like trains and planes, calls etc. and then a separate pair for music listening when in a quiet environment. Given the size of these products, it's easy to carry around 2 or more of them.