Well, when you say "wipe", that means a complete cleaning.
Here's what I suggest:
1. Create a new "administrative" account for your wife. CONSULT WITH HER FIRST as to how she wants the account to be named. Give it a temporary password, which she can change later on.
1a. Also look around the drive for any data files you have stored outside of your home folder. If you want these "gone", put them into the trash and then choose to "secure empty trash".
2. Next, sign out of your account, and sign into your wife's
3. Now, DELETE your old account. IMPORTANT: when you choose to delete an account, the OS offers you the options of either completely erasing the old account, or just archiving it. You want to erase it.
Now, take a "good look around".
At this point, what should be present are:
- Mac OS
- Your wife's new (but yet empty) account
- All the apps that were previously installed
- Anything else which you did not erase
What should be gone are:
- Your old account and all data that was previously stored within
- Any other data files which you removed.
You can now hand the MacBook to your wife.
She can change the original password to one she likes.
She should have before her the previously installed apps.
BE AWARE that she may have to re-register any apps that require registration.
If this process won't do it for you, perhaps it would be best to completely re-initalize the drive, and "start over".