with that info coming directly from apple, i would assume that a 2 or 4 Gm modual can be used in each and any slot. i would pair them tho like all your 4gb in top slots and all your 2gb in bottom.
*i have come to the startling conclusion that my big beefy 27 inch imac is nothing more than a glorified laptop that i cant take anywhere. a mobile processor, mobile graphics chip, and now, laptop memory... *