I have a U3818DW but I use it with a 2013 Mac Pro, no issues. I'd go for it, it's a great display. Prior to that, I had a Late 2015 27" iMac and a U3415W, and that worked fine too. The 3415 was a perfect match in terms of vertical size (physical screen height) but it was obvious that it was non-Retina next to the 5k display of my iMac