I’m in the (apparently pretty common) boat of having one of these beasts and debating whether to just leave the 8GB that shipped with it sitting on the desk. My starting point was
this set of BareFeats tests. Essentially if you have dual channel with either two (properly placed)
or four identical sticks, you get about 23GB/s. If you have mismatched dual-channel (properly placed but differently-sized sticks), you get about 19GB/s. If you install four sticks in the wrong order so you’re in single channel but have both banks available, you get about 13GB/s. Wrong order (single channel) with only two sticks is even lower, down around 10-12GB/s depending on brand.
So obviously matched sticks are best, but you take a
much bigger hit from running single channel than mismatched dual-channel; ~20% vs ~45%.
There is no practical situation where 72GB in single channel (or at lower clock speed) would be better than 64GB in dual channel. Maybe one could artificially contrive some such situation to prove a point, but not in realistic use.
I’m curious about the lower clock speed claims; I haven’t tested yet, but the 8GB stock RAM I pulled says 2666 right on it, so it seems like it shouldn’t reduce the bus speed, and the Barefeats test linked above shows essentially the same performance with 4-32-4-32 as with 3rd party (all 2666) 16-32-16-32.
In any case, it seems pretty obvious that unless your use case involves needing exactly 70GB of physical RAM to avoid swapping you will on average come out ahead nearly all the time with the faster 64GB, but I guess I’m still left wondering, from a speculative standpoint, how much real-world impact a 20% hit in RAM throughput will
really have in day-to-day “general prosumer” computing.