To *do* what? Play it? Edit it? To play it - use quicktime... Edit it? Not really, but if you want, try using FCPx -- but NOT premiere.
I don't think so. It's only got a 10 Gb/s Thunderbolt port. The bandwidth isn't enough to drive 4K at 60Hz. You might have some luck driving it at 30Hz or 24Hz.
not working. Neither with HDMI (1.4) nor Thunderbolt (1). HDMI 1.4(a) should be able to output 4k (2160p) at 24 Hz