A lot of people are recommending the Logitech Z-5500 THX-Certified 5.1 speakers lately (not just in this thread), but I'm wondering if they even read the OP's needs?
They are indeed a nice speaker setup, but there are other factors to consider. First off, the subwoofer is huge. Also, it's a surround setup, so there are 5 speakers in addition to the subwoofer, and this is going to require a lot more space than a 2.1 or monitor setup. The lowest price I've seen on the Z-5500 is $200 plus shipping, and that offer was for a few days only.
The speaker wire is attached, and can't be upgraded (easily). If you're not planning on playing games or watching movies, than surround sound is not necessary. Likewise, if these are things you intend to do, then it's a fab choice.
OP: I've heard good things about the Harmon Kardon speakers you linked. I think if you like the look, you'll very likely be satisified with them.