Someone over at creativecow told me it's best to set the ouput resolution for a sequence correctly in the composition when you first create it (before importing) and that it is better than selecting output resolution in the render que. His explaination was it will take better advantage of AE's resizing algorithms. I'm having a hard time finding evidence to support this. Of course it's best to have settings correct from the start but in my case I want multiple sized outputs (1620x1080, sidebared 1920x1080 & 1270x720). So would that mean for optimum quality I need to do all my work 3 separate times with 3 separate compositions?