I tested both AirPods Pro and Bose QC Earbuds extensively.
Yes the AirPods Pro has better quality mic.
Comfort is subjective.for some Airpods Pro will fit better for some Bose QC Earbuds.
The Bose definitely has MUCH more effective ANC.they are close to ANC level of full sized Bose/Sony headphones.so if you feel AirPods Pro ANC is "so effective" you will be blown away by Bose ANC.I put it this way,AirPods Pro ANC is not really noise cancelling but noise reduction,maybe 60% reduction vs Bose C ANC actually cancells maybe 85% on noises.
and it's not just my opinion if you search reputabl;e reviews they all confirm Bose QC Earbuds is the king of ANC.
Sound Quality? defenitely Bose is better.
What AirPods Pro have are : smaller size,a little easier integration with Apple devices,better quality mic.