So there are a few common quandaries that can arise with the damn finicky bands, in my experience:
1: Sweat siphons nickel ions from the ostensibly hypoallergnic circular plate on the Sport Band, provoking any nickel allergies or invoking a nickel allergy for the underexposed e.g. males - subsequent exposures will then produce quicker irritation as the allergy has “developed” so to speak.
Here you’re mostly f*cked absent a cover for the plate, so you’ll need to find a band absent metallic contact to the wrist in this case, IMO.
2: Moisture-associated skin damage with Sport Band or Solo Loop: excessive moisture brought about by constant, particularly proximal (read: tight and optimal for moisture development or trapping liquid a la soap and such) blockade of the skin will hinder basic cellular renewal & result in skin irritation, atrophy.
Here, it is prudent to keep in mind the skin’s anabolic cycles - outward skin is usually succeeded by novel tissue every month or so. Cease wearing the Apple Watch in any remotely tight position, ensure quality & well above adequate nutrition, rest.
After several weeks, try on a band configuration only slightly looser or begin increasing breaks/cleaning intervals. Rinse and repeat with more caution if irritation develops again.
**** other options:
Sport Loops or breathable mesh-esque bands (braided too) don’t tend to have these issues at remotely the same frequency. Even a little air & a little less metal goes a long way.