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No drivers in MacOS for nvidia cards and nvidia doesn't have MacOS drivers of their own.

It might run under Windows in bootcamp.

It should work fine for AMD graphic cards under MacOS if the eGPU supports the card.
 
No drivers in MacOS for nvidia cards and nvidia doesn't have MacOS drivers of their own.

It might run under Windows in bootcamp.

It should work fine for AMD graphic cards under MacOS if the eGPU supports the card.

If I recall correctly, some people have done some hacks on previous models with T2 chip.
 
If I recall correctly, some people have done some hacks on previous models with T2 chip.

Doing a quick search, the hacks work on High Sierra but not Mojave or later.

I'm not sure if the 16" Macbook Pro comes with Mojave or Catalina ?

I'm not sure if the 16" Macbook Pro will run High Sierra ?
 
The stock GPU in MBP 16” doesn’t even have drivers in 10.15.0 (initial release) for 5XXX series of AMD GPUs. Need 10.15.1+ for GPU drivers for 5300M and 5500M.

If you NEED to run High Sierra, look to another (older) machine to do it.
 
Doing a quick search, the hacks work on High Sierra but not Mojave or later.

I'm not sure if the 16" Macbook Pro comes with Mojave or Catalina ?

I'm not sure if the 16" Macbook Pro will run High Sierra ?

It comes with Catalina.
 
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