I just got my 3G tonight. I've been using it a good bit but not for hour on end. I've noticed that I'm getting a headache and my eyes feel fatigued after just using the screen for a short time. And when I look up my eyes have to adjust to my surroundings like I was cross-eyed or something. I stare at computers all day and I never experience this. Maybe it's a brightness issue? Do you want brighter or less for a well lit room. I also notice its worse when I scroll down while reading websites. I tend to read while scroll and it doesn't seem as smooth on the iPad as with the iPhone or computer. Anyways, I'm not bashing the iPad at all. I love mine! Just want to see if I'm the only one who experiences this and if maybe I can do something about it.