I have the Bose AE2i.
They have a detachable cable. While they're not cheap, you can definitely replace the cable with the inline mic/remote via Bose or third seller via Amazon. With that being said, I've had the AE2is for the past year, and the idea that I might ruin the cable has not never occurred to me. While the cable fits sturdily into the earcup, a tough tug will detach the cable from the earcup. This is convenient for when it gets snagged on things.
When I stow away my headphones in a bag or luggage, I always detach the cable, put it in the pouch that comes with the headphones, then place the headphones into said pouch. I never tightly wrap the cable around anything. Ever. I just place the cable in the pouch without winding it or anything. The cable isn't super long and it hardly ever gets tangled. If it does, it's child's play to fix it.
As for sound coming from the cable rubbing against things, it happens. However, I usually use these headphones while sitting down at a computer or doing work at a desk, so to me it's a non-issue. While these headphones do a good job isolating sound, I wouldn't wear them while walking around because I like to hear what's around me (passerbys, cars, etc.).
The sound quality is decent. If you're liking for a hardcore audiophile experience, you've gotten the wrong set. However, sound is clear and crisp. Phone calls over the iPhone come in clear and people say I sound clear on the other end. The weird thing about wearing these headphones while making phone calls is that you can't really hear yourself talking. For me, it's kinda uncomfortable talking like that, but to each their own.
Honestly, I really, really, like these headphones. I have some Audio Technicas that I adore for when I'm listening to music or watching movies. However, if you're looking for decent sound, decent noise isolation, comfort, and portability, you've definitely chosen a good headset. The AE2is are light and fold up easy, so they're easy to throw into a bag or backpack when you're on the go. They're light and soft around the ears, and you'll easily forget they're there until someone taps you on the shoulder. The inline mic/remote that works on my iPhone and my MBP is a plus.
My only gripe is the overall durability of the headset. The band is fairly thin, so if you have a big head and are stretching it out to the max, I'd question how long it'd last. Aside from that, just take care of your headset (like all your electronics) and I think you'll really like the pair.