Be interesting to see if the Shinjuku offices close. Or if we finally get a proper Apple Store in Yokohama!
Train schedule: 33 min Shinjuku to Yokohama via the Shonan Shinjuku Liner (JR), about 5 more to Sakuragicho (one end of Minato Mirai, where the new Apple presence is to be). 25-30 min Tokyo to Yokohama (Tokaido).
32 min Shibuya to Minato Mirai.
Actually, by far the most convenient is the Tokyo Metro Fukotoshin Line, which has direct service to Sakuragicho Station from Shibuya, Shinjuku and Ikebuburo plus run-through services from the Seibu Ikenbuburo Line and Tobu Tojo Line. It's been said once the run-through services started the number of visitors to Yokohama substantially jumped.