Not really. Preview 38 459/555.
Preview 38 is Safari 11.1 listed string on macOS 10.12.
Interestingly, Safari 11 beta 6 that can be downloaded for El Captian and Sierra is 455/555. The difference is no beacon enabled yet and Subresource integrity under the Security tests.
By comparison: Safari 10.2 currently for macOS 10.12 is 419/555.
WebGL 2 is currently enabled in 10.2 but going under additional testing for 11 (beta 6) and 11.1 (Preview 38)
Safari 10.2 lacks Peer to Peer 0/38 points, Scripting 0/3 for Modules.k
Outside of shoring up Forms, Peer-to-Peer Media Stream recorder and Screen Capture, Writable streams, Audio speech recognition, and possibly Device motion/orientation with WebVR, plus the Web Animations API nothing new features are untouched.
What's always ongoing will be future web standards that are yet to be flushed out like WebGPU (https://gpuweb.github.io/admin/cg-charter.html), updates to current HTML 5.x (5.2/5.3 RC) [if necessary], CSS 1/2/3 full support(https://www.w3.org/Style/CSS/) and possibly SVG 1.2/2.x/MathML, etc.
Nothing drastically is missing, unless you think having Forms support and web applications are a do or die scenario between Safari and Chrome.
Thanks for all the info!