There's a lot of factors to consider.
- If I need multiple SSDs running simultaneously for various purposes (working cache for my vfx software, media source for massive video files, etc), is there any reason to consider installing those in PCI slots vs. slapping a few OWC ThunderBlades on top of the Studio. I'm having a discussion on another forum right now about the potential for improved random read/write speed via PCI vs Thunderbolt.
- The endless debate about whether third party GPUs of any kind will ever work in the Mac Pro.
- Edit to add: whether the Mac Pro has improved thermals, and would allow greater peak sustained performance.
The only silly one I can think of is whether I need wheels...