application specific keyboard settings

looking for a program that will let me have application specific keyboard and/or mouse settings.

primary function would be to replace the command/control substitution (for non-apple keyboards) based on the current (focused) application. This way I can (for example) have the control key act as control when a VM is active, but work as command when in a simple mac application.

it would be nice if I could also do that same with actual keys or combinations of keys and keyboard modifiers.