I Googled and Googled for this answer yesterday before installing but I didn't find anything. So I'm starting a thread to help out anyone in the same boat. The ATI Remote Wonder software seems to work as well for me in Leopard as it did on earlier versions of OS X -- which is to say, perfectly. There aren't any keyboard or keymapping issues so far, and it's a dream for pre-IR Macs like mine that now benefit from the inclusion of Front Row with Leopard. The latest version (2.0.1) of the software is available here. I do wish that ATI would come out with updated drivers, since anything released in December of 2005 could probably use some fine-tuning by now, but it seems to be working smoothly in spite of the lack of updates. It's still PPC-only, however, so Intel users will have to content themselves with the alternatives. Sorry. I personally think the RW is one of the best remote solutions available.