Hi, I have an Apple TV 2 that periodically will not connect to iTunes. I'm running the latest firmware for the ATV, and the latest version of iTunes on a Snow Leopard equipped 17" Intel iMac. iTunes is installed on my local hard disk, however, the media and iTunes library file are on an external Western Digital hd. If I quit iTunes on the Mac and then start it up again the ATV will connect. However, my Mac is upstairs and my ATV is downstairs so this is inconvenient at best. I have not enabled the sleep mode on the Mac because I want to make sure that it's available to the ATV. Nor have I enabled the "Put the hard disk(s) to sleep" mode. However, I believe that the WD hard drive I'm using does have it's own sleep mode that it enters after periods of inactivity (it's one of those "eco" models in a Macalley enclosure). iTunes never has any issues playing music from the drive though even after the drive goes to sleep. The drive just spins up and all is well in iTunes, but not well with the ATV. Hope this gives you all enough info! Thanks in advance for your help!