Audio problem

A few weeks ago I was watching a game on ESPN3.com Now every time we turn on the volume for the computer it starts up the audio for that game. I can't get it to stop. It only will stop after it runs through it all. I get the audio of what I want but they play over each other. Now today it is no longer doing that game but a song my wife was listening to. Unfortunately it starts over a few seconds after it ends. How do I fix this? Thanks for any help.