Hey there. When I bought my Macbook Pro Retina 15", I tried it with my USB 2.0 audio interface (Presonus 22VSL). It worked so good, I got rid of my dedicated PC. However, since using it more, I'm noticing drops in audio and overall USB issues with this device. I may return the interface and try out a new one, but before I do, I wanted to see if anyone has any recommendations for troubleshooting the USB on this thing. I've read some articles that mention killing "KBDMGR.EXE" which was reported to cause dropouts, but these are old articles: http://forums.macrumors.com/showthread.php?t=614302&highlight=bootcamp+audio+interface I'm just curious if anyone has anything I can try. I'm sorta desperate at this point since I really banked on this (a potential foolish thing to have done). I've already set the laptop to max performance, disabled sleeping USB, all drivers are up to date from what I can tell. I did do a USB latency test (provided via Presonus' website), and I notice occasional spikes in latency about a minute apart. If anyone has any suggestions, I'm all ears.