I have tried out close to a dozen apps on OSX and haven't been impressed with any really. Then I found iBank and have been tremendously happy with it. The developers are also quick with information and updates. I used to use Liquid Ledger but did not like it at all (granted, that was before their big 2.0 update which looks significantly improved.).
iBank is sweet. Quicken I always felt was slow and terribly archaic in its style.