Best Mouse and Mousepad Combo for Large Hands

[Matte2]

I would appreciate some recommendations on a wired mouse and mousepad combination that is comfortable for people with large hands. Currently using a Logitech M100 mouse that's on the small side with a mousepad that has an integrated wrist rest. This combination feels kind of awkward on my hands. Should I switch to a mousepad with no wrist rest and what should I look for in a mouse?

 

[Fishrrman]

I'd suggest one of the Logitech "MX" series mice.

They are physically "larger". Should fit a "big hand" very well.

However, they are all wireless mice that use a receiver that plugs into a USB port.
Generally, not a problem...

 

[fhall1]

The Logitech MX Master also uses Bluetooth - no dongle

 

[glenthompson]

I have very large palms and always liked a large mouse. Before switching to the Mac I used a Microsoft mouse that was huge. Mint worked well. After getting used to the Magic Mouse I found it was more comfortable but I hold snd use it very differently than traditional mice.