Wow, with wrist protection, Penultimate just rules them all. I can't believe how well it works! It has become the app of choice now. Wonderful!
Penultimate has really always had the best writing (no lag, looks great on the screen, etc), and their implementation of hand-ignoring is by far the best of all the apps I've tried that have attempted this. All of this, with their simple, intuitive interface, make PU a great choice for quick, easy note-taking.
However, they still have a few things holding them back. Their notebook organization is horrible - almost as bad as their writing is good. They need to steal some ideas from Ghostwriter. If you have more than a couple of notebooks, it is really frustrating and time-consuming to switch between them. The animation here really adds nothing, and it takes up time.
Also, their notes don't look great on the desktop - everything looks too big, especially if you ever need to print out the notes. I wish they would change the default method of saving so that the scaling looked correct.
And then there are little things, such as the ability to use a smaller pen width and different pen colors on screen.
I hope they add these things soon - if so, I doubt I would ever use anything else.