If you have a GTR you can HIRE someone to take notes for you...and why are you even bothering with college

?? Just kidding. But I am jealous.
It is a bit overwhelming. But Microsoft Word actually has a decent notetaking mode built in. And it can record audio as well, and that is a super-great feature to have in ANY notetaking application. Look for ones that will sync what you write with the audio. That way instead of writing down some prof's 10 minute description of the Treaty of Utrecht you can just write "Treaty of Utrecht" and then when you click on it later, boom: there's the audio for you to listen to.
Not all of these applications use iCloud, but using Dropbox or similar services is actually more versatile. Besides, iCloud might end up disappearing just like MobileMe.
And Evernote is great. And if you do audio in Evernote, there are add-ons that will transcribe it.
I'd secon Circus Ponies Notebook as well. It has the added value of being a great research tool for putting together papers, so it's much more than just a take-notes-in-class application. I use it for legal briefs.