Booting to an OS X system on a PPC Mac was sometimes a challenge, but usually doable with a bit of code magic in Open Firmware.
Firewire, no problem at all.
But, since the advent of Intel processors, for the last 12 years, booting through USB is just making sure that your clone is actually a bootable one. It's not directly related to the type of drive hardware that you might use, but the interface itself.
If you were making copies of various different OSes, the Startup Disk preference pane will NOT tell you if a system that SHOULD be bootable, actually will boot. And, you also have to know if that particular Mac is compatible with the version of OS X that you have used for a clone. If it appears in the Startup Disk pane, that's not a guarantee that system is acceptable. I have bootable partitions for Tiger, which does not have Intel code, but will still appear as a choice for booting. It won't boot on any Intel Mac, but is fine on a wide range of PPC Macs. It actually appears in Startup Disk on many Intel Macs, but cannot actually boot. It even appears in the Option-boot picker screen, but again, doesn't actually boot.
I would suspect that your bootable clones may simply not be good copies of a bootable system, or maybe too old for current CCC to correctly make the system bootable, or just systems that are not compatible with the Mac that you are trying to boot.