I have a iMac, it's been partitioned off and vista has been installed. Here is my system info? 2.4 GHz Intel Core 2 Duo Processor 1 GB of 800 MHz DDR2 SDRAM; supports up to 4 GB ATI Radeon HD 2400 XT graphics processor with 128MB of GDDR3 memory Here are the minimum system requirements for fall out 3:Windows XP/Vista 1GB System RAM (XP) / 2GB System RAM (Vista) 2.4 Ghz Intel Pentium 4 or equivalent processor Direct X 9.0c compliant videocard with 256MB RAM (NVIDIA 6800 or better / ATI X850 or better) I don't know if I missed anything. I think it will run but...I'm not positive. Does anyone know?