No, you usually can happily switch the drives between mac models, they just work. There must be something special with your installation that prevented switching. What you observed is highly unusual.My guess is "no." I once moved a HDD from a MacBook Pro to a MacBook. When I tried to boot, I got an error saying something about the system drive not matching the computer model. I assumed that, when you install OS X, it stores information about the particular computer. I had to do a clean installation of OS X and restore from my TMB. That was several versions of OS X ago, though,so you might give it a try if you're curious.
Got both TC and CC clone. Was wondering whether this would save time.
If no one has ever tried this, I'll try it later this year myself and report back.
Personally, I'd shy away from Fusion drives at this point. With fusion, you're relying on two drives - which doubles your chances of failure (generally speaking).
2TB SSD drives are only about $200 now. You'll get better speeds and better resiliency.
I have not done it. Still on the Mac Mini 2009 as have not upgraded yet.
Please report back.