I have a friend that swears you can and he has done this.Not using Skype mind you but he says "Apple to Apple is easy to do" and I admit I have no idea how or if it is possible. Maybe through Ichat? Or what. Anyone know or is this just so much bunk?
iChat is very easy to use. You can use a MobileMe or aol instant messanger account to sign in. Once you have your buddy (friend) on your list you click the camera icon next to their name and iChat will start the video chat.