Had this problem back in January when my wife purchased a Iphone 6s. Tried to restore the Iphone from her older Desktop Imac 2008 with Lion 10.7.5 and Itunes version 12.2.2; she got an error stating that it needed a newer version of Itunes. Clicking update Itunes tells her that her Itunes is up to date. She just tried to backup again and gets the same error. Is there a workaround to this? Just noticed that I mentioned that she has a 5se. Not; she has a Iphone 6s. I have a 5se! Couldn't see how to edit the heading. Should be "Can't backup Iphone 6s to computer"