First off the main thing that's anoying the hell outa me is when you go 'back'.. Safari insists on refreshing the page once it finally gets back. The only solution to this I've found is to disable 3rd party extensions entirely, but I can't do without my AdBlock. Second thing most annoying is in-browswer .pdf and .ppt views.. they're sluggishly-awful compared to Chrome. I really hope Safari 7 fixes these issues.. I tried..