Command-R not Reloading on Macbook Pro 15

are you sure thats still the shortcut to reload a page?

 

It's the right command....try re-setting your PRAm and empty your Safari cache.


I was going to post the link to PRAm re-set, but the site is down.

Shut down your Mac

Restart whilst holding down CMD +OPTION+P+R

Let the Mac boot twice and release the keys on the second chime.

 

PRAM reset won't do anything, that's not among the things that PRAM controls.

OP, take a look in System Preferences -> Keyboard -> Keyboard Shortcuts. Look through the list there and see if you can find anything showing that shortcut (likely something like "Speak Selected Text"). I don't see anything quite matching that on my computer, but I suspect that will reveal the problem. If you find it, simply double-click on the keyboard shortcut shown, and hit the delete key to remove the shortcut.

jW