I have the basic 120GB one and it suits me just fine. I don't run it as a fusion drive, it's a separate partition that has my OS X install and apps on it. For my current needs it is more than adequate since I keep my iTunes library on a high speed SD card that lives permanently in the rear SD card slot of the iMac (that location is simply not suited to regular card access and I already have an external usb reader for my camera's cards).
My install plus apps and the bulk of my day to day work lives on that SSD and it happily sits with more than 40 GB free. I am looking to upgrade at some point in the future to a larger drive, especially since I'm thinking of migrating the windows partition to it (that runs off the internal HD). All other large files that are rarely accessed, or where access time doesn't matter just live on that internal HD and the whole thing is backed up via time machine to an external USB3 drive.
I can highly recommend the LaCie rugged SSD - it's small, it's orange (but that is easy to remove without damaging it if you don't like that) and bus-powered, and the included thunderbolt cable is the ideal length.
I have TRIM support working just fine with it (as you'd expect on the TB bus), and the access speeds are near-native for a SATA3 SSD, which is what is inside the case.
Great, thank you for the information.
I was thinking of trying a Fusion Drive, but TBH, I want more than the 128GB of flash storage Apple offer. I figured I could get the best of both worlds by using an external TB SSD as the boot drive. I'm happy to hear that I should get near-SATA3 speeds over TB.
I will probably purchase the 256GB Lacie rugged SSD, but still not sure on whether the Seagate TB adaptor paired with a 500GB Samsung EVO will work better. I must say that I do prefer the more "complete" look of the Lacie drive (although it will be hidden in the cable management tray anyway).