I use the ASUS Rampage II Gene mATX X58 board. The power supply is a Corsair HX750W.
My mATX case has 5x 120mm fans: 2x on each side, and one on the rear. I'm also using the Corsair H50 CPU water cooler to cool the 920. How I setup is that all four side fans are pulling air in, and the GPUs essentially segment off the case into halves: the two 120s on the right side to help to cooler the GPUs, while the two 120s on the left blow in air that helps cool the memory slots and the northbridge.
I have the rear 120mm blowing out, and the H50's radiator can hold a 120mm on the front and back, so the rear 120mm slot technically has the radiator plus two 120mms. The HX750W also has a 140mm fan to cool the PSU, and the Radeons expel their air mostly through the rear slot (they also expel a little through the top of the card, which the PSU's fan pulls up and out). Thus, in the rear, there are three exit locations for air. Overall, the setup is working really well. The 920 is currently only running at 3.4Ghz, but it's temps are around 40C at idle and the low 50s peak at load. The Northbridge usually peaks at about 52-54C, which for the X58 in this setup is rather good.