CrossOver works for a small handful of older games I play. Plus it runs Winamp for chiptune playback.
First of all, awesomeanother chiptune fan! I love me some mods, XMs, etc. But OSX can play mods too - there's a really useful app called CocoModX that plays all module formats. Don't know about Huelsbecks TFMX format though (that's why I ripped mine from my Amiga to AAC
).