default printer setting for a document

A small but annoying problem: Somehow, each document created in OSX remembers the first printer that it was ever printed on and resets to that option every time it is opened. Does anybody know a way to change this? It doesn't help to change printer setup and save the document - always returns to the original setting next time it's opened. This trips me up at least two or three times a week, sending forms to a printer on the other side of the building that doesn't support two-sided printing.