It's bad at work, I have to constantly wear earplugs when the A.C. is on (and stay in my office when some idiot kicks on the supplemental A.C. making it even colder.) Even with my much improved diet and some exercise, that artificial cold is murder on my sinuses. I'm in constant cold all day (commute and work) so I avoid turning on the A.C. at home unless the humidity is very high.
I imagine we should clean the filters in our ancient A.C.s at home again.
Speaking only for myself here: I have found that a much cleaner diet, the aforementioned hydration, exercise and nasal breathing have stopped most allergies and sinus issues for me.
The Mini split Acs sound great, but way out of my budget.
Yes, very expensive and I put it off for a long time. But at least I'm sleeping through the night now. Over time it'll be worthwhile.