I use it with a mouse often, but usually not at a desk. either in my lap on the couch with a mouse, or at a table. Problem is, simply internet browsing (no flash) REALLY heats up my Macbook. I wonder why I'm so warm, with the cool temperature inside, and then remember I'm using an Apple notebook, which is notorious for heat issues due to being so thin, and having a mediocre cooling system.
Especially when I'm playing AoE3 on it though, it gets REALLY hot (180 F).
all powerful notebooks these days get pretty warm around 50-70 degrees C and Intels chips are made to with stand temps up to 80. the cooling system is actually the hardware's job but i find OS X handles power management quite well. Apple makes the default fan speed quite low for aesthetics but this in turn makes the MacBooks hotter.
just get a fan control app like SMC Fan Control and set it > 2000 rpm. it should fell cooler but it may suck a few minutes of battery life.
I have fan control running at a permanent 3200 RPM.Trust me, it still gets unacceptably hot with simple tasks, over extended periods.
Yeah, I use a mouse with my PowerBook most of the time.