I feel like my deficit in mouse ability with my LH is much lower than, say, my deficit with writing LH. I can do it nearly as well LH without a lot of extra practice as I can RH.
I don't know if that's typical of other people's experience, also?
I could understand then using RH, just because the keyboard/mouse relationship was not really well-designed for sinistrality.
The only thing I seem to have a problem with in that regard is command-tab. Because you can't really select icons with the mouse that way, so you're stuck cycling through them with the keyboard.
Right handed but I mouse with the left.