I don't know if you have a dual CPU or single CPU board, but I have a 4,1 flashed to 5,1, with two W5670 Xeon hexacores, a flashed GTX 980, 64 gb of RAM, and a CalDigit USB 3.0/eSATA card that is running Win 10 Pro 64-bit under bootcamp.
If you can load 8.1 pro into the machine, you can easily upgrade for free to Win 10 pro under the free Microsoft upgrade program at this time. That being said, I must warn you that Win 10 drivers and legacy programs from Win 8.1 may not be fully stable or run at all. We found the hard way that a lot of hardware/software support IT help desks refused to help us after the upgrade to Win 8.1 so I had to spend a lot of time loading drivers/tweaking programs to work with Win 10.
You may also need to install x64 drivers one at a time from a bootcamp thumb drive. This is nor straightforward, nor is it simple, but you can do it if you take the time.
Good luck!