ROTFLOL Every time DP/beta anything comes out and people start running they start asking questions and looking for help in whatever forums they're accustomed to using. There is aways some self ordained internet police officer there who thinks it's their job to tell them there foolish or otherwise wrong for doing so.
Newsflash. I develop software and need to run 10.9DP and Xcode 5. While I care very little about Adobe's products, I would like to know before installing 10.9DP to get my actual work done if Photoshop is going to fail to explode or not.
While I could certainly hack the crap out of the DP and install it in a VM like I did for 10.8 and test it, It's really much easier to backup my main drive and install it than to expend spend all that energy. Unless of course someone else already has tried and is kind enough to ACTUALLY HELP and say what their experience is.
Someday the internet will be free of unhelpful trolls that think they just HAVE to chime in on everything.
With that, Photoshop is running fine for me under 10.9DP1. Including my keyboard shortcuts and save as. I don't use a lot of the more advanced bits of PS though so YMMV.